How duplicate genes provide genetic robustness remains an unresolved question.We have examined the duplicated histone deacetylases Sir2p and Hst1p in Saccharomyces cerevisiae and find that these Serving Pitchers paralogs with non-overlapping functions can provide genetic robustness against null mutations through a substitution mechanism.Hst1p is an
Digital mental health interventions, such as those provided by smartphone applications (apps), show promise as cost-effective approaches to increasing access to evidence-based psychosocial interventions for psychosis.Although it is well known that limited financial resources can reduce the benefits of digital approaches to mental healthcare, the ex
The article is devoted to problems of criminal liability for legalization (laundering) of the money or other property acquired by other persons Tobacco by the criminal way because of evasion of taxes.Identification and suppression of this illegal activity by the staff of tax and law enforcement agencies Swivel Chairs is one of the important directi
The aim was the evaluation of IL-6 concentration in peritoneal lavage fluid of children which underwent Serving Pitchers cholecystectomy to ascertain if there is a difference in early inflammatory response depending on the type of surgical approach (open vs.laparoscopy).The analysis of high-mobility group protein B1 (HMGB1) and heat shock protein 7